ABSTRACT
Background: Patients frequently need a rapid sequenceinduction (RSI) endotracheal intubation technique duringemergencies or electively to protect against aspiration inconditions like pregnancy, abdominal pathologies especiallyobstruction or ileus, neurologic disease, or in difficult airway.Traditionally succinylcholine has been the most commonlyused muscle relaxant for this purpose because of its fast onsetand short duration; unfortunately, it can have serious sideeffects. Rocuronium has been suggested as an alternative tosuccinylcholine for intubation.Methods: This study was done at department of anesthesiaSMBT Institute of Medical Science and Research Center,Dhamangaon Tal. Igatpuri, Nashik, Maharashtra, India. Thepatients were systematically randomized into three groups oftwenty each. Group A: Succinylcholine 1.5 mg/kg, Group B:Rocuronium bromide 0.6 mg/kg &Group C: Rocuroniumbromide 0.9 mg/kg.Intubating conditions, onset of action andadverse effects were observed.Results: It was observed that group A & group C patients hadexcellent intubation conditions with faster onset of action forgroup A patients. Adverse effects were not seen in any of thethree groups.Conclusion: Our study concludes that Succinylcholine is anideal agent for intubation in all surgical procedures. Intubatingconditions of Rocuronium bromide at a dose of 0.9mg/kg(3xED95) is comparable to Succinylcholine 1.5mg/kgat1minute. Rocuronium bromide 0.9mg/kg can be used safelyin patients where succinylcholine is contraindicated.
ABSTRACT
Background: Postoperative sore throat (POST) is a slightcomplication after general anaesthesia. Numerous agents havebeen used as lubricant to lessen the incidence of POST withvariable efficacy.Methods: We compare the incidence of POST with 0.05%betamethasone gel and 2% lignocaine jelly as a lubricant forLMA insertion in patients undergoing general anaesthesia.Sixty subjects were separated randomly into two groups.Patients in Group B (n = 30) had 2.5 ml of 0.05% ofbetamethasone gel while the Group L had 2.5 ml of 2%lignocaine jelly applied on the cuff of LMA. After criterioninduction and insertion of LMA cuff inflated to 60 cm of H2Oand was maintained at the same throughout the surgery.Results: In PACU, patients evaluated about sore throat atimmediate and 24 h post-operative period. POST was not seenin any of the patients of Group B. In group L 13% of thepatients had 1st degree and 3% had 2nd degree of sore-throatin immediate post-operative period. After 24 h 3%patients had1st degree sore-throat and 1% patients had 2nd degree ofsore-throat in Group L patients.Conclusion: We conclude that lubricating cuff of LMA with0.05% of betamethasone gel is efficient in reducing theincidence of POST.